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Table 2 Summary of final panel judgements compared with the IWGDF judgements for all the IWGDF Offloading recommendations

From: Australian guideline on offloading treatment for foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease

No.

Problem

Desirable effects

Undesirable effects

Quality of evidence

Values

Balance of effects

Acceptability

Applicability/ feasibility

Decision

Comments

1a

+

Yes

?

Moderate

+

Trivial

-

Moderate

+

Probably no important uncertainty

+

Favours the intervention

+

Probably yes

+

Probably yes

Adapt

Adapted QoE & control

1b

+

Yes

?

Trivial

+

Trivial

-

Low

+

Probably no important uncertainty

+

Does not favour either intervention or control

+

Probably yes

+

Probably yes

Adapt

Adapted QoE & strength of recommendation

2

+

Yes

+

Moderate

?

Varies

+

Low

-

Possibly important uncertainty

+

Probably favours the intervention

+

Varies

+

Probably yes

Adapt

Adapted control, patient circumstances & foot-device interface

3

+

Yes

?

Varies

+

Small

-

Very low

+

Probably no important uncertainty

+

Favours the intervention

+

Yes

+

Yes

Adapt

Adapted QoE, control, patient circumstances & foot-device interface

4a

+

Yes

?

Don’t know

?

Don’t know

-

Low

-

Possibly important uncertainty

+

Favours the comparison

+

Probably yes

+

Probably yes

Adapt

Adapt QoE & control

4b

+ Yes

+ Small

+ Small

- Very low

+ Probably no important uncertainty

+ Probably favours the intervention

+ Probably yes

+ Probably yes

Adapt

Adapted QoE, intervention & control

5

+

Yes

+

Moderate

+

Small

+

Low

+

Probably no important uncertainty

+

Probably favours the intervention

+

Probably yes

?

Probably yes

Adapt

Adapted intervention

6

+

Probably

yes

+

Moderate

+

Small

+

Low

+

Probably no important uncertainty

+

Probably favours the intervention

+

Probably yes

?

Yes

Adapt

Adapted population

7a

=

=

=

=

=

=

=

=

Adopt

Adopted in screening

7b

=

=

=

=

=

=

=

=

Adopt

Adopted in screening

7c

=

=

=

=

=

=

=

=

Adopt

Adopted in screening

8

=

=

=

=

=

=

=

=

Adopt

Adopted in screening

9

+

Yes

-

Don’t know

-

Don’t know

-

Very low

+

Probably no important uncertainty

+

Favours the intervention

+

Probably yes

+

Probably yes

Adapt

Adapted QoE, intervention & control

  1. Note: +, panel agreed with the original IWGDF judgement; −, panel disagreed with the original IWGDF judgement; ?, panel unsure if agreed with the original IWGDF judgement due to lack of IWGDF information on judgement; =, panel agreed with the original IWGDF judgement during screening (see Table 1); QoE Quality of evidence